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Thoracic Oncology Lab »  Alumni »  Postdoctoral Fellows »  Trevor A. Graham, Ph.D.
Trevor A. Graham, Ph.D.

Trevor A. Graham, Ph.D.

  • Postdoctoral Fellow

Contact Information

Helen Diller Family Comprehensive Cancer Center
Department of Surgery
University of California, San Francisco
2340 Sutter St. Box 1351
San Francisco, CA 94115
[email protected]
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Education

Imperial College London, UK, MSci Mathematics 2002
University College London, UK, MRes Modelling Biological Complexity, 2004
University College London, UK, PhD Mathematical Biology, 2008

Postdoctoral Training

  • Cancer Research UK London Research Institute, UK, Postdoctoral Research Fellow 2008-2011
  • UCSF, CA, USA, Postdoctoral Research Fellow, 2011-current
  • Barts Cancer Centre, QMUL, London, UK, Group leader, autumn 2013-onwards

Research Interests

  • Bioinformatics
  • Clonal evolution in cancer
  • Colon cancer
  • Intestinal stem cells
  • Lung cancer
  • Mathematical biology

Website Links

Biography

I originally trained as a mathematician, and during my PhD and postdoctoral training I spent lots of time in genetics and pathology labs working at the lab-bench. In my day-to-day work I develop and use a variety of mathematical, statistics and wet-lab molecular biology (mainly genetics) techniques. The clonal evolution of cancer has been the focus of my research since the beginning of my PhD training.

Research Overview

I research clonal evolution in cancer. I spend most of time my trying to measure the rate of evolution within cancers and in premalignant lesions. I try to use these measures to predict prognosis for established cancers, and the risk of developing cancer in premalignant lesions. I'm interested in the patterns of evolution that shape carcinogenesis, and these patterns are determined by mutational processes and the histological structure of tissues that constrains clonal expansions.

 

 
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