Biography
Li Tai was a bioinformaticist from 2011 to 2014. He focused primarily in the bioinformatics analysis of micoarray gene expression and Next Generation Sequencing (NGS) data. He is currently a Bioinformatics Scientist at Bina Technologies, Inc.
Prior to UCSF, Li Tai has completed a 6-month theoretical chemistry fellowship with Professor Avinoam Ben-Shaul in the Hebrew University of Jerusalem. They have together developed a simple mathematical model to approximate the 3D size of single-stranded RNA molecules.
Li Tai has also obtained a Ph.D. in Biochemistry from the UCLA in 2010, having worked with Professors William M. Gelbart and Charles M. Knobler. His dissertation is the Physics of DNA, RNA, and RNA-like Polymers. Li Tai's work on the mathematical model of RNA has won him UCLA's George Gregory Research Award in Physical Chemistry in 2009.
He also has a B.A. in Biochemistry from UC Berkeley in 2003.
Research Overview
I have developed a number of Internal Programs for microarray and Next Generation Sequencing (NGS) analysis. We are equipped with Life Technologies SOLiD 5500, Ion Proton, Ion Torrent, and 3730 DNA Analyzer.
Microarray analysis programs are mainly written in MATLAB and Python 3 for data exported by Affymetrix GeneTitan. For NGS, some internal programs are developed to further process the analysis and annotations generated by LifeScope Genomic Analysis Software, ANNOVAR, Strelka, MuTect, Samtools, Picard, etc.